References

Nigella Sativa. (Black Seed oil and Thymoquinone)

Allergies

Herbal treatment of allergic rhinitis: the use of Nigella sativa
Nigella sativa (black seed) oil does not affect the T-helper 1 and T-helper 2 type cytokine production from splenic mononuclear cells in allergen sensitized mice
Clinical and experimental effects of Nigella sativa and its constituents on respiratory and allergic disorders

Anemia

Nigella sativa improves anemia, enhances immunity and relieves iron overload-induced oxidative stress as a novel promising treatment in children having beta-thalassemia major
Effect of black seed oil supplementation on selected immunological, hematological and Iron status parameters in ribavirin treated female albino rats
Immunomodulatory effect of Nigella sativa oil treatment in iron deficiency anemia caused by refractory coeliac disease

Anti-biotic

Black cumin (Nigella sativa) and its constituent (thymoquinone): a review on antimicrobial effects
Structural Characterization, Antimicrobial Activity, and In Vitro Cytotoxicity Effect of Black Seed Oil
Nigella sativa L. (Black Cumin): A Promising Natural Remedy for Wide Range of Illnesses
GC–MS characterisation and antibacterial activity evaluation of Nigella sativa oil against tderse strains of Salmonella

Anti-inflammatory

Effects of Nigella sativa oil extract on inflammatory cytokine response and oxidative stress status in patients with rheumatoid arthritis: a randomized, double-blind, placebo-controlled clinical trial
Antioxidant and Anti-Inflammatory Properties of Nigella sativa Oil in Human Pre-Adipocytes
An Investigation of the Analgesic and Anti-Inflammatory Effects of Nigella sativa Seed Polyphenols
The Anti-Inflammatory Activity of Nigella sativa Balm Sticks

Anti-oxidant

Effect of Nigella sativa on Glucose Concentration, Lipid Peroxidation, Anti-Oxidant Defence System and Liver Damage in Experimentally-Induced Diabetic Rabbits
A New Oleanane Type Saponin from the Aerial Parts of Nigella sativa with Anti-Oxidant and Anti-Diabetic Potential
Antioxidant and Anti-Inflammatory Properties of Nigella sativa Oil in Human Pre-Adipocytes
Antimicrobial, anti-inflammatory and antioxidant activity of Nigella sativa in clinically endometritic cows
Nigella sativa and Thymoquinone: A Natural Blessing for Periodontal Therapy

Antiviral

Protective and antiviral activities of Nigella sativa against avian influenza (H9N2) in turkeys
Prophetic Medicine-Nigella Sativa (Black cumin seeds) – Potential herb for COVID-19?
Thymoquinone: A Promising Natural Compound with Potential Benefits for COVID-19 Prevention and Cure
The effects of Nigella sativa (Ns), Anthemis hyalina (Ah) and Citrus sinensis (Cs) extracts on the replication of coronavirus and the expression of TRP genes family

Asthma

Nigella sativa as an anti-inflammatory agent in asthma
Comparative Immunomodulatory Activity of Nigella sativa L. Preparations on Proinflammatory Mediators: A Focus on Asthma
The possible prophylactic effect of Nigella sativa seed extract in asthmatic patients

Cancer Research

Anticancer Activities of Nigella Sativa (Black Cumin)
Therapeutic Implications of Black Seed and Its Constituent Thymoquinone in the Prevention of Cancer through Inactivation and Activation of Molecular Pathways
Recent advances on the anti-cancer properties of Nigella sativa, a widely used food additive
Anti-tumor properties of blackseed (Nigella sativa L.) extract
Anticancer activity of Nigella sativa (black seed) and its relationship with the thermal processing and quinone composition of the seed
Thymoquinone as a Potential Adjuvant Therapy for Cancer Treatment: Evidence from Preclinical Studies
Antiproliferative and apoptotic effects of proteins from black seeds (Nigella sativa) on human breast MCF-7 cancer cell line

Cardiovascular support

Cardiovascular Effects of Nigella Sativa L. and its Constituents
Cardiac Inotropic Effect of Long-Term Administration of Oral Thymoquinone
Review on Clinical Trials of Black Seed (Nigella sativa ) and Its Active Constituent, Thymoquinone
Effects of two-months Nigella sativa supplementation on cardiac hemodynamics and adrenergic responsiveness

Cognition

The effect of Nigella sativa Linn. seed on memory, attention and cognition in healthy human volunteers
Nigella sativa and Thymoquinone attenuate oxidative stress and cognitive impairment following cerebral hypo perfusion in rats
The Role of Nigella sativa and Its Active Constituents in Learning and Memory
Neuropharmacological effects of Nigella sativa

Covid

Possible therapeutic effects of Nigella sativa and its thymoquinone on COVID-19
Honey and Nigella sativa against COVID-19 in Pakistan (HNS-COVID-PK): A multi-center placebo-controlled randomized clinical trial
Nigella sativa L as a potential phytotherapy for coronavirus disease 2019: A mini review of in silico studies

Diabetes

Effects of Nigella Sativa on Type-2 Diabetes Mellitus: A Systematic Review
How Nigella sativa Seeds Treat Diabetes and Ameliorates Diabetes Complications and Safety Studies: An Over View
Mechanisms of the hypoglycemic and immunopotentiating effects of Nigella sativa L. oil in streptozotocin-induced diabetic hamsters

Hypertension

Mechanisms of the antihypertensive effects of Nigella sativa oil in L-NAME-induced hypertensive rats
The Black Seed, Nigella sativa (Ranunculaceae), for Prevention and Treatment of Hypertension
Nigella sativa and Its Protective Role in Oxidative Stress and Hypertension

Immune system support

A review on therapeutic potential of Nigella sativa: A miracle herb
Nigella sativa: Reduces the Risk of Various Maladies
The Effects of Nigella Sativa on the Immune Disorders

Joint support

Effect of Topical Application of Nigella Sativa Oil and Oral Acetaminophen on Pain in Elderly with Knee Osteoarthritis: A Crossover Clinical Trial
Effect of an orally formulated processed black cumin, from Iranian traditional medicine pharmacopoeia, in relieving symptoms of knee osteoarthritis: A prospective, randomized, double-blind and placebo-controlled clinical trial
Black Cumin (Nigella sativa L.): A Comprehensive Review on Phytochemistry, Health Benefits, Molecular Pharmacology, and Safety
Investigation of the effect of black cumin oil on pain in osteoarthritis geriatric intdiduals
Investigation of the effect of black cumin oil on pain in osteoarthritis geriatric intdiduals

Respiratory Support

Therapeutic effects of black seed oil supplementation on chronic obstructive pulmonary disease patients: A randomized controlled double blind clinical trial
The effects of Nigella sativa on respiratory, allergic and immunologic disorders, evidence from experimental and clinical studies, a comprehensive and updated review

Rheumatoid Arthritis

Immunomodulatory Effect of Nigella sativa Oil on T Lymphocytes in Patients with Rheumatoid Arthritis
Nigella sativa in controlling Type 2 diabetes, cardiovascular, and rheumatoid arthritis diseases: Molecular aspects
Elucidation of molecular mechanisms underlying the protective effects of Thymoquinone against rheumatoid arthritis
Nigella sativa L. (Black Cumin): A Promising Natural Remedy for Wide Range of Illnesses

Weight loss/Obesity

The effect of Nigella sativa on appetite, anthropometric and body composition indices among overweight and obese women: A crossover, double-blind, placebo-controlled, randomized clinical trial
Effects of oral Nigella sativa oil on the expression levels and serum concentrations of adiponectin, PPAR-γ, and TNF-α in overweight and obese women: a study protocol for a crossover-designed, double-blind, placebo-controlled randomized clinical trial
Mitigation of Obesity-Promoted Diseases by Nigella sativa and Thymoquinone
The effects of Nigella sativa L. on obesity: A systematic review and meta-analysis

Elderberry (Sambucas nigra)

Anti-bacteria

Elderberry is anti-bacterial, anti-viral and modulates the immune system: anti-bacterial, anti-viral and immunomodulatory non-clinical (in-vitro) effects of elderberry fruit and flowers (Sambucus nigra): a systematic review
ABSTRACT: Elderberry (Sambucus nigra) is anti-bacterial, anti-viral and modulates the immune system
Bioactive properties of Sambucus nigra L. as a functional ingredient for food and pharmaceutical industry
IN SILICO STUDY DEMONSTRATES MULTIPLE BIOACTIVE COMPOUNDS OF Sambucus PLANT PROMOTE DEATH CELL SIGNALING PATHWAY VIA FAS RECEPTOR

Anti-depressant

Antidepressant activities of Sambucus ebulus and Sambucus nigra
Antidepressant activities of Sambucus ebulus and Sambucus nigra
Beta-Glucan as Wall Material in Encapsulation of Elderberry (Sambucus nigra) Extract
Bioactive properties of Sambucus nigra L. as a functional ingredient for food and pharmaceutical industry

Anti-viral

A Review of the Antiviral Properties of Black Elder (Sambucus nigra L.) Products
A Review of the Antiviral Properties of Black Elder ( Sambucus nigra L.) Products: Antiviral Properties of Black Elder ( Sambucus nigra L.)
Antiviral properties of Elderberry
Antiviral and healing potential of Sambucus nigra extracts

Cancer

A Comparative Evaluation of the Anticancer Properties of European and American Elderberry Fruits
The effect of Sambucol, a black elderberry-based, natural product, on the production of human cytokines: I. Inflammatory cytokines
Advanced research on the antioxidant and health benefit of elderberry (Sambucus nigra) in food – a review

Colds and flu

Sambucus nigra (black elder) as alternative treatment for cold and flu
Anti-influenza activity of elderberry (Sambucus nigra)
Inhibition of Several Strains of Influenza Virus in Vitro and Reduction of Symptoms by an Elderberry Extract (Sambucus nigra L.) during an Outbreak of Influenza B Panama
Black elderberry (Sambucus nigra) supplementation effectively treats upper respiratory symptoms: A meta-analysis of randomized, controlled clinical trials
Elderberry Supplementation Reduces Cold Duration and Symptoms in Air-Travellers: A Randomized, Double-Blind Placebo-Controlled Clinical Trial

Covid

The effects of Sambucus nigra berry on acute respiratory viral infections: A rapid review of clinical studies
Myth Busters: Dietary Supplements and COVID-19
Wild Sambucus nigra L. from north-east edge of the species range: A valuable germplasm with inhibitory capacity against SARS-CoV2 S-protein RBD and hACE2 binding in vitro
Elderberry for prevention and treatment of viral respiratory illnesses: a systematic review
Seven recommendations to rescue the patients and reduce the mortality from COVID-19 infection: An immunological point of view

Immune support

Elderberry (Sambucus nigra L.) Fruit Extract Alleviates Oxidative Stress, Insulin Resistance, and Inflammation in Hypertrophied 3T3-L1 Adipocytes and Activated RAW 264.7 Macrophages
Effects of Sambucus nigra and Aronia melanocarpa extracts on immune system disorders within diabetes mellitus
Concentration of Bioactive Compounds from Elderberry (Sambucus nigra L.) Juice by Nanofiltration Membranes

Respiratory Support

Black elderberry (Sambucus nigra) supplementation effectively treats upper respiratory symptoms: A meta-analysis of randomized, controlled clinical trials
Elderberry Supplementation Reduces Cold Duration and Symptoms in Air-Travellers: A Randomized, Double-Blind Placebo-Controlled Clinical Trial
The effects of Sambucus nigra berry on acute respiratory viral infections: A rapid review of clinical studies
Inhibitory activity of a standardized elderberry liquid extract against clinically-relevant human respiratory bacterial pathogens and influenza A and B viruses